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24 February 2012

Guideline Development And Objectives

Guideline Development


The Development Group for this Clinical Practice Guidelines (CPG) was from the Ministry of Health (MOH), Ministry of Higher Education and private sector. They consisted of paediatric endocrinologists, paediatricians, adult endocrinologists, a geriatrician, a family medicine specialist, public health physicians and a pharmacist. There was active involvement of the Review Committee during the process of development of these guidelines.

Literature search was carried out at the following electronic databases: PUBMED/MEDLINE, Cochrane Database of Systemic Reviews (CDSR), International Health Technology Assessment websites, Journal full text via OVID search engine, Database of Abstracts of Reviews of Effectiveness and Cochrane Controlled Trials Register (Refer to Appendix 1 for Search Terms). In addition, the reference lists of all retrieved articles were searched to identify relevant studies. Experts in the field were also contacted to identify further studies. All searches were conducted between 20 January 2009 and 11 August 2010. This date period should be considered the starting point for searching of new evidence for future updates to these guidelines.

Reference was also made to other guidelines on Growth Hormone e.g. American Association of Clinical Endocrinologists Medical guidelines For Clinical Practice for Growth Hormone Use in Adults and Children- 2003 update; American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Growth Hormone Use in Growth Hormone Deficient Adults and Transition Patients Children- 2009 update; Guidelines for the Availability of Human Growth Hormone (hGH) as a Pharmaceutical Benefit, Department of Health and Ageing, Australia, July 2008; Consensus Statement on the Management of the GH-Treated Adolescent in the Transition to Adult Care, Society of European Jornal of Endocrinology, 2005; Update of Guidelines for The Use of Growth Hormone in Children: The Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee, The Journal of Pediatrics, October 2003; Consensus guidelines for the Diagnosis and Treatment of Growth Hormone Deficiency in Childhood and Adolescence: Summary Statement of the GH Research Society, European Journal of Endocrinology 2005; and Consensus Guidelines for the Diagnosis and Treatment of Adults with Growth Hormone Deficiency: Summary Statement of the Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency 1998. These CPGs were evaluated using the Appraisal of Guidelines for Research and Evaluation (AGREE) prior to them being used as references.

For further reading, please download the CPG below...


  arrowGrowth Hormone.pdf (English - pdf - 3319 Kb)



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